Photobiomodulation of the Dorsal Root Ganglion for the Treatment of Low Back Pain: A Pilot Study
Laser irradiation caused an immediate decrease in low back pain post-procedure similar to pain reduction caused by lidocaine injection.
OPEN FILEThis pilot, open-protocol study examined whether scalp application of red and near-infrared (NIR) light-emitting diodes (LED) could improve cognition in patients with chronic, mild traumatic brain injury (mTBI).
Participants reported improved sleep, and fewer post-traumatic stress disorder (PTSD) symptoms, if present. Participants and family reported better ability to perform social, interpersonal, and occupational functions.
OPEN FILERetrospective Analysis of Two Different Doses of Photobiomodulation Combined with Rehabilitation Therapy as a Therapeutic Protocol for Canine Degenerative Myelopathy
The authors acknowledge the limitations of a retrospective review. However, the data reviewed shows a significant difference in progression from Sym Onset to NAP and to time of euthanasia between these two PBMt dosage groups, and is suggestive of a similar difference between the HD group and the historical data presented. Further studies are warranted.
OPEN FILETranscranial Photobiomodulation Prevents Anxiety and Depression via Changing Serotonin and Nitric Oxide Levels in Brain of Depression Model Mice: A Study of Three Different Doses of 810nm Laser
Our results demonstrated that NIR TPBM had an anti-anxiety and anti-depressive effect in CRS mice, which is probably linked to increasing 5-HT and decreasing NO levels in the PFC and Hipp areas.
OPEN FILETherapeutic Effects of 10-HzPulsed Wave Lasers in Rat Depression Model: A Comparison Between Near-Infrared and Red Wavelengths
This study showed that non-invasive tLLLT using 10-Hz pulsed NIR laser light was as effective as Citalopram and more effective than red laser in the treatment of depressive-like behaviors and may help improve tLLLT as an alternative non-pharmacological treatments of psychological disorders such as depression.
OPEN FILETranscranial Infrared Laser Therapy Improves Clinical Rating Scores After Embolic Strokes in Rabbits
This study shows that laser treatment improved behavioral performance if initiated within 6 hours of an embolic stroke and the effect of laser treatment is durable.
OPEN FILELow?level laser therapy reduces time to ambulation in dogs after hemilaminectomy: a preliminary study
Low-level laser therapy in combination with surgery decreases the time to ambulation in dogs with T3-L3 myelopathy secondary to intervertebral disk herniation
OPEN FILEEfficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials
We show that LLLT reduces pain immediately after treatment in acute neck pain and up to 22 weeks after completion of treatment in patients with chronic neck pain.
OPEN FILEEffect of Diode Laser in the Treatment of Patients with Nonspecific Chronic Low Back Pain: A Randomized Controlled Trial
This study demonstrated that the use of diode laser (980 nm) with large diameter spot size, in association with exercise therapy, appears to be effective. Such treatment might be considered a valid therapeutic option within rehabilitation programs for nonspecific CLBP.
OPEN FILEThe Mechanistic Basis for Photobiomodulation Therapy of Neuropathic Pain by Near Infrared Laser Light
These in vitro and in vivo studies indicate that treatment with an irradiance/fluence rate at 270mW/ cm2 or higher at the level of the nerve can rapidly block pain transmission.
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