Internal Dosimetry: Combining Simulation with Phantom and Ex Vivo Measurement

As expected, the first-order experiments under-estimated the beam attenuation, but Monte Carlo results served as an accurate prediction of ex vivo observation. Dose delivered at therapeutic depths are up to 2 and 3 orders of magnitude less than those delivered to the surface. With enough data using a variety of skin, tissue, and bone thicknesses, this type of analysis will yield a full dosimetric profile.

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Calculating the Energy Density of a Therapy Laser

Here are some key physics concepts that you must understand when buying a therapy laser: power and power density, wavelength, mode of delivery (continuous wave, pulsed and superpulsed), energy and energy density. This article will help you calculate the energy density of a therapy laser.

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The Fluence Effects of Low-Level Laser Therapy on Inflammation, Fibroblast-Like Synoviocytes, and Synovial Apoptosis in Rats with Adjuvant-Induced Arthritis

LLLT with low fluence is highly effective in reducing inflammation to sites of injury by decreasing the numbers of FLS, inflammatory cells, and mediators in the CFA-induced arthritic model. These data will be of value in designing clinical trials of LLLT for RA.

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808 nm Wavelength Light Induces a Dose-Dependent Alteration in Microglial Polarization and Resultant Microglial Induced Neurite Growth

These data suggest that the Arndt–Schulz law as applied to PBM for a specific bioassay does not hold true in cells with a spectrum of responses, and that PBM can alter microglial phenotype across this spectrum in a dose-dependent manner. These data are therefore of important relevance to not only therapies in the CNS but also to understanding of PBM effects and mechanisms.

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The Optics of Human Skin

An integrated review of the transfer of optical radiation into human skin is presented, aimed at developing useful models for photomedicine.

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