Internal Dosimetry: Combining Simulation with Phantom and Ex Vivo Measurement
As expected, the first-order experiments under-estimated the beam attenuation, but Monte Carlo results served as an accurate prediction of ex vivo observation. Dose delivered at therapeutic depths are up to 2 and 3 orders of magnitude less than those delivered to the surface. With enough data using a variety of skin, tissue, and bone thicknesses, this type of analysis will yield a full dosimetric profile.
OPEN FILECalculating the Energy Density of a Therapy Laser
Here are some key physics concepts that you must understand when buying a therapy laser: power and power density, wavelength, mode of delivery (continuous wave, pulsed and superpulsed), energy and energy density. This article will help you calculate the energy density of a therapy laser.
OPEN FILEThe Fluence Effects of Low-Level Laser Therapy on Inflammation, Fibroblast-Like Synoviocytes, and Synovial Apoptosis in Rats with Adjuvant-Induced Arthritis
LLLT with low fluence is highly effective in reducing inflammation to sites of injury by decreasing the numbers of FLS, inflammatory cells, and mediators in the CFA-induced arthritic model. These data will be of value in designing clinical trials of LLLT for RA.
OPEN FILE808 nm Wavelength Light Induces a Dose-Dependent Alteration in Microglial Polarization and Resultant Microglial Induced Neurite Growth
These data suggest that the Arndt–Schulz law as applied to PBM for a specific bioassay does not hold true in cells with a spectrum of responses, and that PBM can alter microglial phenotype across this spectrum in a dose-dependent manner. These data are therefore of important relevance to not only therapies in the CNS but also to understanding of PBM effects and mechanisms.
OPEN FILEThe Optics of Human Skin
An integrated review of the transfer of optical radiation into human skin is presented, aimed at developing useful models for photomedicine.
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