Low-Level Laser Irradiation Precondition for Cardiac Regenerative Therapy

LLLI preconditioning provides a promising approach to maximize the efficacy of cardiac cell-based therapy. Although many studies have reported possible molecular mechanisms involved in LLLI preconditioning, the exact mechanisms are still not clearly understood.

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Photobiomodulation with 630 plus 810 nm wavelengths induce more in vitro cell viability of human adipose stem cells than human bone marrow derived stem cells

Our study demonstrated that PBM with the combined 630+810 nm lasers significantly stimulated cell viability, and significantly decreased PDT and apoptosis of hBM-MSCs and hASCs in vitro. We reported new in vitro evidence where PBM administered at 630 nm (one and two times, 0.6 and 1.2 J/cm2) and 630+810 nm (three times, 2.4 J/cm2) significantly increased hASC cell viability compared to its control and the PBM-treated hBM-MSC groups.

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Effect of platelet-rich plasma, low-level laser therapy (650 nm) or their combination on the healing of Achilles tendon in rabbits: a histopathological study

However, the treatments combining PRP and LLLT showed significant results (P<0.05). Our results demonstrate a decrease in the time of tendon regeneration by using the two therapies combined, accelerating the healing process.

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Tenogenic induction of equine mesenchymal stem cells by means of growth factors and low-level laser technology

In conclusion, the present study might furnish significant suggestions for developing an efficient approach for tenocyte induction since the external administration of bFGF2 and TGF?3, along with LLLT, influences the differentiation of PB-MSCs towards the tenogenic fate.

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Analysis of experimental tendinitis in rats treated with laser and platelet rich plasma therapies by Raman spectroscopy and histometry

Treatment with PRP combined with irradiation at 830 nm resulted in a larger number of fibroblasts and increased concentration of type I collagen, thus accelerating the healing of the injured tendon.

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